WebNursing mothers: Small amounts of dimenhydrinate are excreted in breast milk. Because of the ... Dosing Considerations The GRAVOL IM dosage form is designed for intramuscular use only and must not be used intravenously (IV) unless it has been diluted (see Intravenous Dilution Instructions below). Assessment & Drug Effects 1. Use side rails and supervise ambulation; drug produces high incidence of drowsiness. 2. Note: Tolerance to CNS depressant effects usually occurs after a few days of drug therapy; some decrease in antiemetic action may result with prolonged use. 3. Monitor for dizziness, … See more Precise mode of antinauseant action not known, but thought to involve ability to inhibit cholinergic stimulation in vestibular and associated … See more Narrow-angle glaucoma, prostatic hypertrophy. Safe use during pregnancy (category B), lactation, or in children <2 y is not established. See more Chiefly in prevention and treatment of motion sickness. Also has been used in management of vertigo, nausea, and vomiting associated with radiation sickness, … See more Note: Give 30–60 min before treatment, then repeat 90 min after treatment, and again in 3 h to prevent radiation sickness. See more
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