Nettet17. mar. 2024 · In our view, machine-learning approaches for inferring isoform-specific function should respond to three main issues: (i) they should not rely on supervised learning, which is limited by our current state of knowledge about isoform functions; (ii) they should not associate GO terms to genes rather than isoforms; and (iii) they should … NettetThe .gov means it's official. Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you're on a federal government site.
UniProt
Nettet24. mar. 2024 · Ontological analysis of genes at the top 10% TPM value revealed the most significant enrichment in the Mouse Gene Atlas database to be NAc (N = 205; adjusted p-value = 5.8e-64), which was expected. Nettet24. mar. 2024 · Ontological analysis of genes at the top 10% TPM value revealed the most significant enrichment in the Mouse Gene Atlas database to be NAc (N = 205; … qwerkywriter typewriter
Q8HWB0 - UniProt
Nettet19. nov. 2024 · The accurate landscape of transcript isoforms plays an important role in the understanding of gene function and gene regulation. However, building complete transcripts is very challenging for short reads generated using next-generation sequencing. Fortunately, isoform sequencing (Iso-Seq) using single-molecule sequencing … NettetAPPRIS identifies a principal isoform for 85% of the protein-coding genes in the GENCODE 7 release for ENSEMBL. Analysis of the APPRIS data shows that at least 70% of the alternative (non-principal) variants would lose important functional or structural information relative to the principal isoform. Nettet27. jul. 2011 · Endosome, multivesicular body. By similarity. Note: Localizes mainly to the plasma membrane. In the presence of SORL1, shifts to vesicular structures, including trans-Golgi network, endosomes and multivesicular bodies. By similarity. qwert64asfghjl