Pulk1 s555
WebNov 25, 2024 · As mentioned above, we confirmed the autophagy activation signaling by measuring pAMPK (T172), pULK1 (S757), pULK1(S555), pS6 (S235/236) and Atg5-12 conjugation. When mice were treated with HCQ to block autophagy flux, besides p62 and LC3II accumulation, we also observed that Atg5-12 conjugated form was increased in the … WebJul 9, 2024 · Search worldwide, life-sciences literature Search. Advanced Search
Pulk1 s555
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WebNov 11, 2024 · Mouse and human mIDH1 glioma cells exhibited increased expression of pULK1-S555, enhanced conversion of LC3I to LC3II, and decreased expression of p62, … WebFeb 1, 2024 · Western blot analysis exhibits the effect of Alda-1 on the phosphorylation of ULK1 with high glucose exposure. G: Representative gel blots of pULK1and β-actin (used as loading control) with specific antibodies; H:ULK1-to-β-actin;I: pULK1-s757-to β-actin;J: pULK1-s555-to β-actin;K: pULK1-s317-toβ-actin.All proteins were normalized to β-actin.
WebFeb 5, 2024 · In this study, C2C12 myotubes were maintained at 37 °C or exposed to 40 °C (HT) for 2 h, and harvested immediately or following 2, 8, or 24 h of recovery. Two hours of HT immediately increased pAMPK (T172; p = 0.001), and subsequently increased pULK1 (S555) at 2 h of recovery (p = 0.028). WebNov 1, 2024 · First, Lcn2 reduced pULK1 S555, increased pULK1 S757 and reduced LC3-II levels determined by Western blotting. We validated the use of DQ-BSA to assess autolysosomal protein degradation and this together with MagicRed cathepsin B assay indicated that Lcn2 reduced lysosomal degradative activity.
WebAnti-phospho ULK1 Antibody (Ser777) from rabbit, purified by affinity chromatography; Synonyms: Serine/threonine-protein kinase ULK1, Serine/threonine-protein kinase … WebBackground Two related serine/threonine kinases, UNC-51-like kinase 1 and 2 (ULK1, ULK2), were discovered as mammalian homologs of the C. elegans gene unc-51 in …
WebSep 28, 2024 · Therefore, we overexpressed wild type BRSK2 in HEK293T cells and measured changes in pULK1 S317 and S555 following treatment with increasing doses of GW296115 for 2 h.
WebULK1 was similar between healthy and dystrophic muscles, however, pULK1 S555 was decreased by 0.5-fold (p < 0.05) in D2-mdx compared to DBA and the ratio was similar … children\u0027s books on bugs and insectsWebFeb 1, 2024 · Basal phosphorylation of pULK1(S555) was upregulated through an AMPK-mediated mechanism in HT29-H cells whereas pAMPKα (T172) was downregulated in … children\u0027s books on balletWebMar 1, 2024 · WT and Ulk1/2 −/− MEFs were treated with dsDNA (4 μg/ml) for the indicated time interval, and lysates were immunoblotted for pULK1 S555, ULK, STING, and β‐actin. J Control, cGAS KO, and STING KO THP1 cells were treated with dsDNA (4 μg/ml) for the indicated time interval, and lysates were immunoblotted for cGAS, STING, pTBK1, … children\u0027s books on communitygovernors opioid summit maineWebNational Center for Biotechnology Information children\u0027s books on belongingWebAfter 30 min of treatment with palmitate, primary hepatocytes from WT mice had increases in the phosphorylation of ULK1 S555, but this effect was not observed in S108A-KI mice (Fig. 4 B and C). Furthermore, the downstream substrate of ULK1, ATG14, had unaltered S29 phosphorylation by palmitate treatment in either group but was modestly reduced in … governors opposed to mandateWebCell Signaling Technology Inc rabbit monoclonal anti pulk1 s555 Rabbit Monoclonal Anti Pulk1 S555, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz … governors on truck engines